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MethodsWe searched for randomised controlled trials or longitudinal observational studies in patients with lung cancer, regardless of histology or stage at presentation, that measured the effect of quitting smoking after diagnosis on the risk of all cause mortality, cancer specific mortality, development of a second primary tumour, or recurrence. We searched CINAHL (from 1981), Embase (from 1980), Medline (from 1966), Web of Science (from 1966), and CENTRAL (from 1977) to December 2008, using search strategies developed with the support of an information specialist that included exploded MeSH terms and also text words relating to smoking and lung cancer. Because of the large volume of studies identified from the search, we separately used two types of filter for study design in databases that returned a high number of studies. Firstly, we filtered search returns for randomised controlled trials in Medline and Web of Science by Cialis Generic Best Price
using database specific filters. Secondly, we separately filtered search returns for longitudinal observational studies in Embase and Medline by using “prognosis specificity” database specific filters and in Web of Science by using text words relating to the study design. All searches were combined in a reference manager database and duplicates removed. We also searched the reference lists of included studies.

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